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Major Study Reinforces Link Between PPI Use, Kidney Problems
Studies continue to put a harsh light on proton pump inhibitors (PPIs), which are medications used to treat acid reflux disease. The latest one further strengthens the belief among researchers that there is a significant link between PPI use and an increased risk for kidney disease as well as kidney failure.
According to a study that was presented at a November 2017 meeting of the American Society of Nephrology (nephrology is an area of medicine focused on the kidneys), people who use PPIs are at as high as a 33 percent increased risk of suffering kidney problems that those who don’t use the medications. Researchers performed a meta-analysis of more than 536,000 people.
In 2016, the Journal of the American Medical Association (JAMA) published a study that also showed an increased risk of kidney problems after using PPIs. Researchers conducting this study looked at the medical records of nearly 10,000 people. After comparing the records of those who took PPIs with those who did not, the researchers found that PPI users were up to 50 percent more likely to develop kidney issues than non-users
People across the country are suing the manufacturers of PPIs. They allege that they developed severe kidney conditions after taking the medications, and that the manufacturers failed to warn them of the risks. Plaintiffs in these lawsuits claim that they would have either used a different type of acid reflux medication or had their kidney health monitored if they had known of those risks.